I ka hoʻomaka ʻana o ka makahiki 2025, ua hōʻike nā mea noiʻi mai ke Kulanui o Wakinekona a me Brigham and Women's Hospital (kahi haukapila aʻo o ke Kula Lapaʻau ʻo Harvard) i kahi ʻano hana like ʻole no ka mālama ʻana i ka maʻi o Alzheimer - inhaling.xenonkinoea, ʻaʻole ia e pale wale i ka neuroinflammation a hōʻemi i ka atrophy o ka lolo, akā hoʻonui pū i nā mokuʻāina neuronal pale.

Xenona me ka Neuroprotection

ʻO ka maʻi Alzheimer ka maʻi neurodegenerative maʻamau i loko o ke kanaka, a ʻo kona kumu i manaʻo ʻia e pili ana i ka hōʻiliʻili ʻana o ka protein tau a me ka protein beta-amyloid i loko o ka lolo. ʻOiai ua loaʻa nā lāʻau lapaʻau e hoʻāʻo e wehe i kēia mau mea ʻawaʻawa, ʻaʻole maikaʻi lākou i ka hoʻolohi i ka piʻi ʻana o ka maʻi. No laila, ʻaʻole maopopo loa ke kumu o ka maʻi a me ka mālama ʻana.

Ua hōʻike nā haʻawina i ka inhaledxenonhiki ke hele i ka pale koko-lolo a hoʻomaikaʻi nui i ke kūlana o nā ʻiole me nā hiʻohiʻona maʻi o Alzheimer ma lalo o nā kūlana hoʻokolohua.Ua māhele ʻia ka hoʻokolohua i ʻelua pūʻulu, ua hōʻike ʻia kahi hui o nā ʻiole i ka hōʻiliʻili ʻana o ka protein a ʻo ka hui ʻē aʻe i loaʻa i ka pūʻulu protein beta-amyloid. Ua hōʻike nā hopena hoʻokolohua ʻaʻole i hoʻoikaika wale ka xenon i nā ʻiole, akā hoʻolaha pū i ka pane pale o microglia, he mea nui ia no ka hoʻomaʻemaʻe ʻana i nā proteins tau a me beta-amyloid.

He mea hou kēia ʻike hou, e hōʻike ana e hiki ke hana ʻia nā hopena neuroprotective ma ke komo ʻana i ke kinoea inert. ʻO kahi palena nui ma ke kahua o ka noiʻi a me ka mālama ʻana o Alzheimer he mea paʻakikī loa ka hoʻolālā ʻana i nā lāʻau lapaʻau e hiki ai ke hele i ka pale koko-lolo, axenonhiki ke hana i keia.

Nā noi lāʻau ʻē aʻe o xenon

1. Anesthesia and analgesia: Ma ke ano he kinoea anesthetic maikai,xenonhoʻohana nui ʻia ma muli o ka wikiwiki o ka induction a me ka hoʻihoʻi ʻana, ka paʻa o ka cardiovascular maikaʻi a me ka liʻiliʻi o nā hopena ʻaoʻao;

2. Ka hopena neuroprotective: Ma waho aʻe o ka hopena lapaʻau kūpono i ka maʻi o Alzheimer i ʻōlelo ʻia ma luna, ua aʻo ʻia ka xenon e hōʻemi i ka pōʻino o ka lolo ma muli o ka neonatal hypoxic-ischemic encephalopathy (HIE);

3. Ka hoʻololi ʻana o ke kino a me ka pale ʻana:Xenonhiki ke kōkua i ka pale ʻana i nā mea hāʻawi mai ka ʻeha ischemia-reperfusion, he mea nui loa ia no ka hoʻomaikaʻi ʻana i ka holomua o ka hoʻololi ʻana;

4. Ka 'ike 'ana o ka radiotherapy: Ua hō'ike mai kekahi mau ha'awina mua e hiki i ka xenon ke ho'onui i ka na'au o ka ma'i koko i ka radiotherapy, e hā'awi ana i ka ho'olālā hou no ka mālama 'ana i ka ma'i 'a'ai;