Ua hoʻohana ʻia ʻo Ethylene oxide (EO) i ka disinfection a me ka sterilization no ka manawa lōʻihi a ʻo ia wale nō ka mea sterilant gas kemika i ʻike ʻia e ka honua ʻo ia ka mea hilinaʻi loa. I ka wā ma mua,ʻokikene ʻokikeneua hoʻohana nui ʻia no ka disinfection a me ka sterilization ma ka pae ʻoihana. Me ka hoʻomohala ʻana o ka ʻenehana ʻoihana hou a me ka automation a me ka ʻenehana akamai, hiki ke hoʻohana palekana ʻia ka ʻenehana sterilization ethylene oxide i nā ʻoihana lapaʻau e sterilize i nā mea lapaʻau kikoʻī e makaʻu ana i ka wela a me ka makū.

Nā ʻano o ka ethylene oxide

ʻEtilena ʻokikeneʻo ia ka lua o ka hanauna o nā mea hoʻomaʻemaʻe kemika ma hope o ka formaldehyde. ʻO ia kekahi o nā mea hoʻomaʻemaʻe anu maikaʻi loa a ʻo ia ka lālā koʻikoʻi o nā ʻenehana sterilization haʻahaʻa haʻahaʻa nui ʻehā.

He hui epoxy maʻalahi ka Ethylene oxide. He kinoea kala ʻole ia ma ka mahana o ka lumi a me ke kaomi. ʻOi aku kona kaumaha ma mua o ka ea a he ʻala ether ʻala. He lapalapa a pahū ka Ethylene oxide. Ke loaʻa i ka ea he 3% a 80%ʻokikene ʻokikene, ua hoʻokumu ʻia kahi kinoea pahū i hui pū ʻia, kahi e ʻā a pahū paha ke hōʻike ʻia i nā lapalapa ahi. ʻO ka nui o ka ethylene oxide i hoʻohana pinepine ʻia no ka disinfection a me ka sterilization he 400 a 800 mg/L, aia i loko o ka pae like ʻole o ka lapalapa a me ka pahū i ka lewa, no laila pono e hoʻohana me ke akahele.

Hiki ke hoʻohui ʻia ka ethylene oxide me nā kinoea inert e like mekalapona ʻokikenema ka lakio o 1:9 e hana i kahi hui pale pahū, ʻoi aku ka palekana no ka disinfection a me ka sterilization.ʻEtilena ʻokikenehiki ke polymerize, akā ma ke ʻano laulā, lohi ka polymerization a hana nui ʻia ma ke ʻano wai. I nā hui ʻana o ka ethylene oxide me ke kalapona dioxide a i ʻole nā ​​​​hydrocarbons fluorinated, hana lohi ka polymerization a ʻoi aku ka liʻiliʻi o ka pahū ʻana o nā polymers paʻa.

Kumumanaʻo o ka Sterilization Ethylene Oxide

1. Alkylation

Ke ʻano hana oʻokikene ʻokikeneʻO ka alkylation ka mea nui i ka pepehi ʻana i nā microorganism like ʻole. ʻO nā wahi o ka hana he sulfhydryl (-SH), amino (-NH2), hydroxyl (-COOH) a me hydroxyl (-OH) i loko o nā protein a me nā molekala nucleic acid. Hiki i ka Ethylene oxide ke hana i kēia mau hui e hana i nā hopena alkylation, e hoʻolilo ana i kēia mau macromolecules biological o nā microorganism i mea hana ʻole, a laila e pepehi ana i nā microorganism.

2. Kāohi i ka hana o nā enzymes olaola

Hiki i ka Ethylene oxide ke kāohi i ka hana o nā enzyme like ʻole o nā microorganism, e like me ka phosphate dehydrogenase, cholinesterase a me nā oxidases ʻē aʻe, e pale ana i ka hoʻopau ʻana o nā kaʻina hana metabolic maʻamau o nā microorganism a alakaʻi i ko lākou make.

3. Ka hopena pepehi i nā microorganisms

ʻO nā mea ʻeluaʻokikene ʻokikeneHe ikaika ka hopena microbicidal o ke kinoea a me ka wai. I ka hoʻohālikelike ʻana, ʻoi aku ka ikaika o ka hopena microbicidal o ke kinoea, a hoʻohana nui ʻia kona kinoea i ka disinfection a me ka sterilization.

He sterilant ākea ākea ka Ethylene oxide i loaʻa ka hopena pepehi a me ka hoʻopau ikaika i nā kino hoʻolaha bacteria, nā spores bacteria, nā fungi, a me nā virus. Ke hoʻopili ʻia ka ethylene oxide me nā microorganism, akā loaʻa i nā microorganism ka wai lawa, ʻo ka hopena ma waena o ka ethylene oxide a me nā microorganism he hopena mua maʻamau. ʻO ka nui e hoʻopau ai i nā microorganism i mahi ʻia maʻemaʻe, ʻo ke piʻo hopena he laina pololei ma ka waiwai semi-logarithmic.

Ka laulā noi o ka sterilization ethylene oxide

ʻEtilena ʻokikeneʻaʻole ia e hōʻino i nā mea i hoʻomaʻemaʻe ʻia a he komo ikaika kona. ʻO ka hapa nui o nā mea i kūpono ʻole no ka sterilization ma o nā ʻano maʻamau hiki ke hoʻomaʻemaʻe ʻia a hoʻomaʻemaʻe ʻia me ka ethylene oxide. Hiki ke hoʻohana ʻia no ka sterilization o nā huahana metala, endoscopes, dialyzers a me nā mea lapaʻau hoʻolei ʻia, disinfection ʻoihana a me ka sterilization o nā lole like ʻole, nā huahana plastik, a me ka disinfection o nā mea ma nā wahi ahulau maʻi lele (e like me nā lole fiber kemika, ka ʻili, ka pepa, nā palapala, a me nā pena ʻaila).

ʻAʻole hōʻino ka Ethylene oxide i nā mea i hoʻomaʻemaʻe ʻia a he ikaika kona komo ʻana. ʻO ka hapa nui o nā mea i kūpono ʻole no ka sterilization ma o nā ʻano maʻamau hiki ke hoʻomaʻemaʻe ʻia a hoʻomaʻemaʻe ʻia me ka ethylene oxide. Hiki ke hoʻohana ʻia no ka sterilization o nā huahana metala, endoscopes, dialyzers a me nā mea lapaʻau hoʻolei ʻia, disinfection ʻoihana a me ka sterilization o nā lole like ʻole, nā huahana plastik, a me ka disinfection o nā mea ma nā wahi ahulau maʻi lele (e like me nā lole fiber kemika, ka ʻili, ka pepa, nā palapala, a me nā pena ʻaila).

Nā mea e pili ana i ka hopena sterilization oʻokikene ʻokikene

Hoʻopilikia ʻia ka hopena sterilization o ka ethylene oxide e nā kumu he nui. I mea e hoʻokō ai i ka hopena sterilization maikaʻi loa, ma o ka hoʻomalu pono ʻana i nā kumu like ʻole hiki iā ia ke hoʻokani maikaʻi i kāna kuleana i ka pepehi ʻana i nā microorganism a hoʻokō i kāna kumu o ka disinfection a me ka sterilization. ʻO nā kumu nui e pili ana i ka hopena sterilization: ka noʻonoʻo ʻana, ka mahana, ka haʻahaʻa pili, ka manawa hana, a pēlā aku.