Ua hoʻohana ʻia ʻo Ethylene oxide (EO) i ka disinfection a me ka sterilization no ka manawa lōʻihi a ʻo ia wale nō ka sterilant kinoea kemika i ʻike ʻia e ka honua ʻo ia ka mea hilinaʻi loa. I ka wā kahiko,ethylene oxideua hoʻohana nui ʻia no ka disinfection a me ka sterilization ʻoihana. Me ka hoʻomohala ʻana o ka ʻenehana ʻenehana hou a me ka automation a me ka ʻenehana akamai, hiki ke hoʻohana pono ʻia ka ʻenehana sterilization ethylene oxide i nā keʻena olakino e hoʻomaʻemaʻe i nā mea lapaʻau pololei e makaʻu nei i ka wela a me ka wai.

Nā hiʻohiʻona o ka ethylene oxide

Ethylene oxideʻo ia ka lua o ka hanauna o nā disinfectants kemika ma hope o formaldehyde. ʻO ia kekahi o nā disinfectant anu maikaʻi loa a me ka lālā koʻikoʻi o nā ʻenehana sterilization haʻahaʻa haʻahaʻa nui.

ʻO ka Ethylene oxide kahi hui epoxy maʻalahi. He kinoea kala ʻole ma ka lumi wela a me ke kaomi. Ua ʻoi aku ke kaumaha ma mua o ka ea a loaʻa kahi ʻala eter ʻala. ʻO ka Ethylene oxide he mea pahū a pahū. Ke loaʻa ka ea 3% a 80%ethylene oxide, hoʻokumu ʻia kahi kinoea hui pū ʻia, e ʻā a pahū paha ke ʻike ʻia i nā lapalapa ahi. ʻO ka hoʻohana maʻamau o ka ethylene oxide no ka disinfection a me ka sterilization ʻo 400 a 800 mg / L, aia i loko o ka pae wela a pahū i ka lewa, no laila e hoʻohana ʻia me ka akahele.

Hiki ke hoʻohui ʻia ka Ethylene oxide me nā kinoea inert e like mekalapona kalaponai ka lakio o 1:9 e hana i kahi hui pahū-hōʻoia, ʻoi aku ka palekana no ka disinfection a me ka sterilization.Ethylene oxidehiki i ka polymerize, akā ma ke ʻano he lohi ka polymerization a loaʻa ka nui ma ke ʻano wai. I loko o nā hui ʻana o ka ethylene oxide me ka carbon dioxide a i ʻole ka fluorinated hydrocarbons, hiki mai ka polymerization me ka mālie a ʻaʻole hiki ke pahū nā polymer paʻa.

Kumu o ka Ethylene Oxide Sterilization

1. Alkylation

ʻO ke ʻano hana o kaethylene oxidei ka pepehi ʻana i nā ʻano microorganism ka nui o ka alkylation. ʻO nā pūnaewele o ka hana he sulfhydryl (-SH), amino (-NH2), hydroxyl (-COOH) a me ka hydroxyl (-OH) i loko o ka protein a me nā molekala nucleic acid. Hiki i ka Ethylene oxide ke hoʻoulu i kēia mau pūʻulu i nā hopena alkylation, e hana ana i kēia mau macromolecules olaola o nā microorganism i mea ʻole, a laila pepehi i nā microorganism.

2. Kāohi i ka hana o nā enzyme olaola

Hiki i ka Ethylene oxide ke pale i ka hana o nā enzymes like ʻole o nā microorganisms, e like me ka phosphate dehydrogenase, cholinesterase a me nā oxidase ʻē aʻe, ke keʻakeʻa nei i ka hoʻopau ʻana i nā kaʻina metabolic maʻamau o nā microorganism a alakaʻi i ko lākou make.

3. Ka hopena pepehi i nā microorganisms

ʻeluaethylene oxideHe hopena microbicidal ikaika ka wai a me ke kinoea. I ka hoʻohālikelike, ʻoi aku ka ikaika o ka hopena microbicidal o ke kinoea, a hoʻohana mau ʻia kāna kinoea i ka disinfection a me ka sterilization.

ʻO ka Ethylene oxide kahi sterilant ākea ākea e loaʻa ai ka hopena pepehi a me ka hoʻoulu ʻole ʻana i nā kino hoʻopulapula bacteria, bacterial spores, fungi, a me nā maʻi. Ke hoʻopili ʻia ka ethylene oxide me nā microorganisms, akā lawa ka wai i loko o nā microorganisms, ʻo ka hopena ma waena o ka ethylene oxide a me nā microorganism he hopena maʻamau maʻamau. ʻO ka pānaʻi e hoʻopau ai i nā microorganism moʻomeheu maʻemaʻe, ʻo ka pihi hopena he laina pololei ma ka waiwai semi-logarithmic.

Ka laulā noi o ka ethylene oxide sterilization

Ethylene oxideʻaʻole ia e hōʻino i nā mea sterilized a ikaika ke komo. ʻO ka hapa nui o nā mea i kūpono ʻole no ka sterilization ma nā ʻano maʻamau hiki ke hoʻomaʻemaʻe ʻia a hoʻopaʻa ʻia me ka ethylene oxide. Hiki ke hoʻohana ʻia no ka sterilization o nā huahana metala, endoscopes, dialyzers a me nā lāʻau lapaʻau disposable, disinfection ʻoihana a me ka sterilization o nā lole like ʻole, nā huahana plastik, a me ka disinfection o nā mea i nā wahi maʻi maʻi maʻi (e like me nā lole fiber kemikal, ʻili, pepa, palapala, a me nā kiʻi ʻaila).

ʻAʻole hoʻopōʻino ʻo Ethylene oxide i nā mea sterilized a ikaika ke komo ʻana. ʻO ka hapa nui o nā mea i kūpono ʻole no ka sterilization ma nā ʻano maʻamau hiki ke hoʻomaʻemaʻe ʻia a hoʻopaʻa ʻia me ka ethylene oxide. Hiki ke hoʻohana ʻia no ka sterilization o nā huahana metala, endoscopes, dialyzers a me nā lāʻau lapaʻau disposable, disinfection ʻoihana a me ka sterilization o nā lole like ʻole, nā huahana plastik, a me ka disinfection o nā mea i nā wahi maʻi maʻi maʻi (e like me nā lole fiber kemikal, ʻili, pepa, palapala, a me nā kiʻi ʻaila).

Nā kumu e pili ana i ka hopena sterilization oethylene oxide

Hoʻopili ʻia ka hopena sterilization o ka ethylene oxide e nā kumu he nui. I mea e hoʻokō ai i ka hopena sterilization maikaʻi loa, ma ka hoʻomalu pono ʻana i nā ʻano mea like ʻole e hiki ai iā ia ke hana maikaʻi i kāna kuleana i ka pepehi ʻana i nā microorganism a hoʻokō i kāna kumu o ka disinfection a me ka sterilization. ʻO nā kumu nui e pili ana i ka hopena sterilization ʻo: ka ʻike, ka mahana, ka haʻahaʻa pili, ka manawa hana, etc.